Cnidium Monnieri (Shi Chuang Zi) naturally increases nitric oxide release, which powerfully increases the production of cGMP. Cyclic Guanosine Monophosphate (cGMP) is the key in obtaining and sustaining a powerful erection. cGMP relaxes the muscles around the penis, which makes it possible for the cells in the penis to take in blood, thus allows you to experience a proper erection.
Chen J, Chiou WF, Chen CC, Chen CF. Institute of Clinical Medicine, National Yang-Ming University, and National Research Institute of Chinese Medicine, Taipei, Taiwan, Republic of China.
Must Read: What is Homeopathy?
PURPOSE: We investigated the cavernosal relaxant effect of osthole, a coumarin isolated from Cnidium monnier (L.) Cusson which has been long used in China as a herbal medicine to improve male sexual dysfunction. MATERIALS AND METHODS: Strips of rabbit corpus cavernosum were precontracted with phenylephrine. Corporal relaxation evoked by osthole was then determined in the absence and presence of nitric oxide synthase inhibitor (L-NAME), soluble guanylate cyclase inhibitor (ODQ), cyclooxygenase inhibitor (indomethacin), tetradotoxin, and after endothelium deprivation. RESULTS: Corpus cavernosal strips showed relaxation in response to osthole (0.1 approximately 30 microM) in a dose-dependent manner. These effects were reduced partially but significantly by pretreatment with L-NAME, ODQ and by endothelial disruption. However, they were not affected by indomethacin and tetradotoxin treatment. Osthole pretreatment (from 1 to 30 microM) enhanced the sodium nitroprusside (0.3 microM)-induced relaxation of corpus cavernosum in a dose-dependent manner to a maximum of 3 times the pretreatment level at 30 microM osthole. However, this effect was abolished in the presence of zaprinast. Additionally, a higher concentration of osthole (30 microM) also enhanced forskolin-induced relaxation. CONCLUSION: The data suggested that osthole possesses a relaxant effect on rabbit corpus cavernosal tissues which is attributable to the release of NO from sinusoidal endothelium and to the potentiation of the cGMP and/or cAMP signal mediating relaxation of cavernosal smooth muscle by inhibiting phosphodiesterase.
Dr Spence PentlandDr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland.
Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer.
In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families.
Dr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland.
Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer.
In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families.
Further demonstrating his commitment to reproductive health, he is a devoted member of IAAC (Infertility Awareness Association), CFAS (Canadian Fertility and Andrology Society), and ASRM (American Society for Reproductive Medicine).
As the former president of the Traditional Chinese Medicine Association of British Columbia and the provincial BC TCM quality assurance committee, Dr. Pentland is well respected by peers and patients alike. He remains actively involved in educating healthcare colleagues and the public on the powerful benefits of Chinese medicine & acupuncture, working steadily on the integration of ancient Daoist wisdom into modern western life as a way to build awareness about reproductive health. This compassionate expertise is reflected in patient testimonials.
When not helping others start their families, Spence can be found spending time with his own--his adoring wife Chantal and their two beautiful sons. “I am very proud to be part of the team of professionals at Yinstill. We are all dedicated to raising the bar in the field of complimentary and alternative reproductive medicine. Nothing is more important than family,” he says.
Professional Development Certifications
Combining TCM and IVF to Improve Clinical Outcomes - Jane Lyttleton
Treating Complex Gynecological Conditions with Evidence-based Acupuncture - Elisabet Stener-Victorin
High-Performance Summit - Darren Hardy
Acupuncture during Pregnancy: safe and ethical practice - Claudia Citkovitz
Treating Irregular Menstrual Bleeding - Sharon Weizenbaum
Management of High Risk Pregnancy Conditions - David Bray
Physiology & Pathology of Gynecology - Giovanni Maciocia
Treatment protocols for Menopause and Endometriosis - Kiiko Matsumoto
Chinese medicine approach to the treatment of Poor Ovarian Reserve - Brandon Horn
Clinical problems and solutions in Oriental Reproductive medicine - Dr. Daoshing Ni
Treatment strategies for PCOS, Weight Loss, & type 2 Diabetes - Sharon Weizenbaum
Allergic and Autoimmune diseases - Mazin Al-Khafaji
Acupuncture in Pregnancy & Childbirth - Debra Betts
Treating Infertility with Chinese medicine - Bob Flaws
Masters class in Diagnosis - Bob Flaws
East meets West in Reproductive medicine - Mike Berkley
The Infertility Cure - Chinese wellness program - Randine Lewis
Men’s Health and Fertility - Peter Deadman
Integrating acupuncture and IVF - Diane Cridennda and Dr. Paul Magarelli
Treatment of Infertility with Chinese medicine - Jane Lyttleton
Yang School lecture series Part 1 - Dr. Liu Fang
Advanced acupuncture in pregnancy - Jean Levesque
Certified Western herbalist - Packard School of Nutrition
Courageous conversations - Justice Institute
Biology of Empowerment - Dr. Lee Pulos
Secrets of Chinese Pulse Diagnosis - Bob Flaws and Honora Lee Wolfe
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