Categories: Mens fertility Research

Nutrition affects sertoli cell production, the cells in the testis that produce sperm

Conclusion: foetal to pubertal subnutrition is accompanied by changes in testicular structure and lower Sertoli cell numbers in adult life, strongly suggesting lower daily sperm production.

Contents To test whether undernutrition during foetal to pre-pubertal life would have long lasting effects on testicular histology in adult male offspring, eleven adult Sprague-Dawley pregnant rats were divided into two groups: Control group, n = 4, fed ad libitum, during gestation and lactation (until 25 day post-partum). Underfed group pregnant females (n = 7) were kept in cages where only dams had access to food (standard rat chow, 33.5% of ad libitum intake of Control group pregnant dams). After parturition, litters were adjusted to either 14 (Underfed group) or eight (Control group) pups. Mothers were weighed weekly. At 25 day of age pups were weaned, housed at four animals per cage, fed ad libitum and weighed weekly until euthanized at 100 day of age. Testes were processed for standard histology and morphometrical evaluation. At weaning, mother weight was lower in Underfedthan in Control group (mean +/- SD): 214.1 +/- 26.2 g vs 361.9 +/- 33.1 g. Body weight at 100 days of age (254 +/- 26.9 g vs 342.4 +/- 10.2 g, p </= 0.001), testicular weight (1.29 +/- 0.16 g vs 1.45 +/- 0.13 g, p = 0.03), number of Sertoli cells per seminiferous tubule cross section (18.2 +/- 1.2 vs 20.2 +/- 1.3, p </= 0.01) and per testis (30.5 +/- 4.2×10(6) vs 36.0 +/- 5.4×10(6)) were lower (p < 0.05) in Underfed than in Control group. This is the first report stating that foetal to pubertal subnutrition is accompanied by changes in testicular structure and lower Sertoli cell numbers in adult life, strongly suggesting lower daily sperm production.
Dr Spence Pentland

Dr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland. Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer. In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families. Dr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland. Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer. In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families. Further demonstrating his commitment to reproductive health, he is a devoted member of IAAC (Infertility Awareness Association), CFAS (Canadian Fertility and Andrology Society), and ASRM (American Society for Reproductive Medicine). As the former president of the Traditional Chinese Medicine Association of British Columbia and the provincial BC TCM quality assurance committee, Dr. Pentland is well respected by peers and patients alike. He remains actively involved in educating healthcare colleagues and the public on the powerful benefits of Chinese medicine & acupuncture, working steadily on the integration of ancient Daoist wisdom into modern western life as a way to build awareness about reproductive health. This compassionate expertise is reflected in patient testimonials. When not helping others start their families, Spence can be found spending time with his own--his adoring wife Chantal and their two beautiful sons. “I am very proud to be part of the team of professionals at Yinstill. We are all dedicated to raising the bar in the field of complimentary and alternative reproductive medicine. Nothing is more important than family,” he says. Professional Development Certifications Combining TCM and IVF to Improve Clinical Outcomes - Jane Lyttleton Treating Complex Gynecological Conditions with Evidence-based Acupuncture - Elisabet Stener-Victorin High-Performance Summit - Darren Hardy Acupuncture during Pregnancy: safe and ethical practice - Claudia Citkovitz Treating Irregular Menstrual Bleeding - Sharon Weizenbaum Management of High Risk Pregnancy Conditions - David Bray Physiology & Pathology of Gynecology - Giovanni Maciocia Treatment protocols for Menopause and Endometriosis - Kiiko Matsumoto Chinese medicine approach to the treatment of Poor Ovarian Reserve - Brandon Horn Clinical problems and solutions in Oriental Reproductive medicine - Dr. Daoshing Ni Treatment strategies for PCOS, Weight Loss, & type 2 Diabetes - Sharon Weizenbaum Allergic and Autoimmune diseases - Mazin Al-Khafaji Acupuncture in Pregnancy & Childbirth - Debra Betts Treating Infertility with Chinese medicine - Bob Flaws Masters class in Diagnosis - Bob Flaws East meets West in Reproductive medicine - Mike Berkley The Infertility Cure - Chinese wellness program - Randine Lewis Men’s Health and Fertility - Peter Deadman Integrating acupuncture and IVF - Diane Cridennda and Dr. Paul Magarelli Treatment of Infertility with Chinese medicine - Jane Lyttleton Yang School lecture series Part 1 - Dr. Liu Fang Advanced acupuncture in pregnancy - Jean Levesque Certified Western herbalist - Packard School of Nutrition Courageous conversations - Justice Institute Biology of Empowerment - Dr. Lee Pulos Secrets of Chinese Pulse Diagnosis - Bob Flaws and Honora Lee Wolfe View Articles and Blog Posts by Dr. Pentland Read Dr. Pentland's Success Stories Become Spence's friend on facebook

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