Summary We conducted the first US study to compare semen quality among study centres using standardized methods and strict quality control. We present data on semen quality in partners of 493 pregnant women recruited through prenatal clinics in four US cities during 1999-2001. Sperm concentration, semen volume and motility were determined at the centres and morphology was assessed at a central laboratory. While between-centre differences in sperm morphology and sample volume were small, sperm concentration and motility were significantly reduced in Columbia, MO (MO) relative to men in New York, NY, Minneapolis, MN and Los Angeles, CA; total number of motile sperm was 113 x 10(6) in MO and 162, 201 and 196 x 10(6) in CA, MN and NY respectively. Differences among centres remained significant in multivariate models that controlled for abstinence time, semen analysis time, age, race, smoking, history of sexually transmitted disease and recent fever (all p-values less than 0.01).
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We hypothesized that poorer sperm concentration and motility in MO men relative to other centres might be related to agricultural pesticides that are commonly used in the mid-west. We investigated this hypothesis by conducting a nested case-control study within the MO cohort. We selected 25 men in this cohort for whom all semen parameters (concentration, % normal morphology and % motile) were low as cases and an equal number of men for whom all semen parameters were within normal limits as controls. We measured metabolites of eight non-persistent, current-use pesticides in urine samples the men had provided at the time of semen collection. Pesticide metabolite levels were elevated in cases compared with controls for the herbicides alachlor and atrazine, and for the insecticide diazinon (2-isopropoxy-4-methyl-pyrimidinol) (p-values for Wilcoxon rank test = 0.0007, 0.012, and 0.0004 for alachlor, atrazine and diazinon respectively). Men with higher levels of alachlor or diazinon were significantly more likely to be cases than men with low levels [odds ratios (OR) = 30.0, 16.7 for alachlor and diazinon respectively], as were men with atrazine over the limit of detection (OR = 11.3). These associations between current-use pesticides and reduced semen quality suggest that agricultural chemicals may have contributed to the reduced semen quality seen in fertile men from mid-Missouri.
Dr Spence PentlandDr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland.
Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer.
In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families.
Dr. Pentland is founder of The IVF Acupuncture Group of Greater Vancouver, available 7 days a week for on site embryo transfer and acupuncture treatments at the Pacific Centre for Reproductive Medicine (PCRM) and Genesis Fertility Centre. “The integrated relationship I have established with these clinics is something that I value very much as it expands my knowledge, gives me the opportunity to reach more people, and helps me better understand how to support women on their journey toward family.” says Dr. Pentland.
Dr. Pentland, along with Dr. Jeffrey Roberts of The Pacific Centre for Reproductive Medicine (PCRM), and Dr. Christine Sutton of the University of British Columbia, authored research published in Fertility & Sterility on the stress reducing effects of acupuncture when administered in the weeks leading up to an IVF embryo transfer.
In 2015 Spence published BEING FERTILE - 10 Steps to Help You Overcome the Struggles of Infertility, Get Pregnant, and Create a Happy, Healthy Family. A book written to provide hope, tools and resources for women and couples experiencing difficulty starting or expanding their families.
Further demonstrating his commitment to reproductive health, he is a devoted member of IAAC (Infertility Awareness Association), CFAS (Canadian Fertility and Andrology Society), and ASRM (American Society for Reproductive Medicine).
As the former president of the Traditional Chinese Medicine Association of British Columbia and the provincial BC TCM quality assurance committee, Dr. Pentland is well respected by peers and patients alike. He remains actively involved in educating healthcare colleagues and the public on the powerful benefits of Chinese medicine & acupuncture, working steadily on the integration of ancient Daoist wisdom into modern western life as a way to build awareness about reproductive health. This compassionate expertise is reflected in patient testimonials.
When not helping others start their families, Spence can be found spending time with his own--his adoring wife Chantal and their two beautiful sons. “I am very proud to be part of the team of professionals at Yinstill. We are all dedicated to raising the bar in the field of complimentary and alternative reproductive medicine. Nothing is more important than family,” he says.
Professional Development Certifications
Combining TCM and IVF to Improve Clinical Outcomes - Jane Lyttleton
Treating Complex Gynecological Conditions with Evidence-based Acupuncture - Elisabet Stener-Victorin
High-Performance Summit - Darren Hardy
Acupuncture during Pregnancy: safe and ethical practice - Claudia Citkovitz
Treating Irregular Menstrual Bleeding - Sharon Weizenbaum
Management of High Risk Pregnancy Conditions - David Bray
Physiology & Pathology of Gynecology - Giovanni Maciocia
Treatment protocols for Menopause and Endometriosis - Kiiko Matsumoto
Chinese medicine approach to the treatment of Poor Ovarian Reserve - Brandon Horn
Clinical problems and solutions in Oriental Reproductive medicine - Dr. Daoshing Ni
Treatment strategies for PCOS, Weight Loss, & type 2 Diabetes - Sharon Weizenbaum
Allergic and Autoimmune diseases - Mazin Al-Khafaji
Acupuncture in Pregnancy & Childbirth - Debra Betts
Treating Infertility with Chinese medicine - Bob Flaws
Masters class in Diagnosis - Bob Flaws
East meets West in Reproductive medicine - Mike Berkley
The Infertility Cure - Chinese wellness program - Randine Lewis
Men’s Health and Fertility - Peter Deadman
Integrating acupuncture and IVF - Diane Cridennda and Dr. Paul Magarelli
Treatment of Infertility with Chinese medicine - Jane Lyttleton
Yang School lecture series Part 1 - Dr. Liu Fang
Advanced acupuncture in pregnancy - Jean Levesque
Certified Western herbalist - Packard School of Nutrition
Courageous conversations - Justice Institute
Biology of Empowerment - Dr. Lee Pulos
Secrets of Chinese Pulse Diagnosis - Bob Flaws and Honora Lee Wolfe
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